Select Reports

Key U.S. Patent Issues on Expression Pathology’s Liquid Tissue® Technology
The patent claims methods to enable protein analysis in FFPE tissue for clinical research and diagnostics.

Scientists Identify new Congenital Neutropenia Syndrome and Causative Gene Mutation
Scientists have discovered a rare disorder in which children lack sufficient infection-fighting white cells which is caused due to mutations in the G6PC3 gene.

Galapagos Selects Pre-Clinical Candidate Drug for Cachexia
Galapagos’ pre-clinical candidate G100192 has demonstrated successful Proof of Concept in animal studies.

Cell Death from Cytomegalovirus may Bring new Life to Treatment of Retinal Disease
A recent $1.3 million grant from the National Eye Institute is enabling studies of what's likely the body's well-intended effort to stop cytomegalovirus retinitis.

University of Maryland School of Medicine Researchers Identify Common Gene Variant Linked to High Blood Pressure
Researchers have identified STK39 gene that produces protein involved in regulating how the kidneys process salt.

New Tool Developed to Predict Colorectal Cancer Risk
A newly launched online tool for calculating colorectal cancer risk is based on a new risk-assessment model developed by researchers at NCI.

Technique for Creating Authentic Rat Embryonic Stem Cells
The technique licensed exclusively by Stem Cell Sciences, is expected to allow the generation of rat ES cells to create genetically modified animals.

Biomarkers Summit, London, UK
02 February 2009 - 03 February 2009

SMi’s Biomarkers Summit, the 2nd in the biomarkers series offers a unique opportunity to hear about the latest developments from industry leaders. Bringing together knowledge and expertise, it’s designed to create the perfect setting for the exchange of ideas and networking opportunities.

MedChem Europe, Berlin, Germany
23 February 2009 - 25 February 2009

The 5th annual MedChem Europe conference will cover methods of drug discovery, including Fragment-Based Lead Detection and the field of Chemogenomics and Combichem. Co-located with Screening Europe and ADMET Europe, and sharing an exhibition, registration will allow access to all 3 meetings.


Biomarkers Congress, Manchester, UK
26 February 2009 - 27 February 2009

The event attracts 200 senior attendees from pharmaceutical, biotechnology, diagnostics, clinical research companies in Europe. Topics include Biomarker Discovery, Validation, Molecular Diagnostics, Data Integration, Modelling and Bioinformatics, Imaging, Clinical Development and Toxicity Biomarkers.


Isotope Tracers in Metabolic Research: Principles and Practice of Kinetic Analysis, Little Rock, AR, USA
04 May 2009 - 08 May 2009

A week-long course in the theory and practice of isotopic tracers (stable and radioactive) for the study of metabolism in man and animals using mass spectrometry and NMR. The course will emphasize isotopomer analysis for metabolic flux rates and metabolic regulation.

Senior Research Associate
Momenta Pharmaceuticals
Cambridge, MA, USA

Product Manager
Millipore Corporation
Billerica, MA, USA

Director of Marketing
KLAnderson & Assoc.
Torrance, CA, USA

Laboratory Technician
KLAnderson & Assoc.
Torrance, CA, USA

Project Manager
Evolution Life Science
South East, UK

Sales Specialist
Evolution Life Science
Cambridge/East Midlands, UK

Bioanalytical Scientist
Evolution Life Science
North West, UK

Pre/Post Inside Sales Applications Manager - Analytical Instruments and Supplies
Agilent Technologies
Wilmington, DE, USA

Peptide Purification Lab
New England Peptide, Inc.
Gardner, MA, USA

Sales Representative
New England Peptide, Inc.
Gardner, MA, USA

Director, Marketing & Sales
Growing Biotech Company
Middleton, WI - relocation provided

Director, Marketing & Sales
Growing Biotech Company
Middleton, WI - relocation provided

Knowledge of personal energy requirements in college students
University of Nevada, Las Vegas

This study explored whether university students were able to estimate their energy requirements within a range of calories equal to predicted Estimated Energy Requirements (EER) two standard deviations. Students significantly underestimated their EER by 700 calories (p<.001). Fewer males than expected were able to estimate energy requirements as compared to females, 41.3% vs. 20.6%, ?2 (1) = 7.236, p=.007.

Knowledge of personal energy requirements in college students
University of Nevada, Las Vegas

This study explored whether university students were able to estimate their energy requirements within a range of calories equal to predicted Estimated Energy Requirements (EER) two standard deviations. Students significantly underestimated their EER by 700 calories (p<.001). Fewer males than expected were able to estimate energy requirements as compared to females, 41.3% vs. 20.6%, ?2 (1) = 7.236, p=.007.

No Impact of Dietary Iodine Restriction in Short Term Development of Hypothyroidism Following Fixed Dose Radioactive Iodine Therapy for Graves Disease
*Department of Endocrinology ,Nuclear Medicine and Clinical Biochemistry, Christian Medical College Vellore India 632004

To study the outcomes at 6 months after fixed dose 131I therapy for Graves’ disease (GD) with an iodine restricted diet.
  


Utilizing GC and GCxGC Coupled with Time-of-Flight Mass Spectroscopy (TOMFS) for the Analysis of Metabolomic Samples

Mark Libardoni, Technical Director - Life Science and Chemical Analysis Centre, LECO Corporation, speaking at Advances in Metabolic Profiling 2007


Alterations in Cardiolipin Profile Link Diabetic Cardiomyopathy and Mitochondrial Dysfunction in Murine Models of Diabetes: A Shotgun Lipidomics Study

Xianlin Han, Washington University, speaking at Advances in Metabolic Profiling 2007

High-Throughput Method for Dynamic Measurements of Cellular Viability Using a FLUOstar OPTIMA
BMG LABTECH

We show that the propidium iodide (PI) assay performed on the FLUOstar OPTIMA from BMG LABTECH is a very useful tool for monitoring neuronal viability. It allows a complete analysis of the dynamics of the response to a specific substance.
Numerous parameters, including lag times and rates of death can be assessed using this PI method. The FLUOstar OPTIMA is a flexible microplate reader able to record PI fluorescence over very long periods.

A global abstract analysis of selected histone-modifying enzymes using AKS
Active Motif

A global abstract analysis (GAA) was performed on twelve histone-modifying enzymes (ASH1, CARM1, CBP, CKII, EZH2, MSK1, MST1, NSD1, PCAF, RIZ1, SIRT2 and TIP60) to demonstrate how this approach can help uncover biological relationships, scientific information, and overall publication trends from PubMed abstracts and related biological databases. This GAA study showed that published research of histone-modifying enzymes has increased significantly since 2001 and that many reported studies have fo

Multiplexed Diagnostics 2008 Market Report
Published May 2008

Multiplexed diagnostics are the wild west of medicine. Technology is established, regulation is limited and the number of new biomarkers exploding. First-movers are grabbing biomarker territories, combining independent measurements for efficiency and mining molecules for multivariate panels. All the while demand is high for improving diagnoses and predicting responses to treatment. The challenges, however, are uncertain reimbursement, unclear business models and ever-intensifying competition. On